Vitamin D is actually a powerful hormone that tells over 200 different genes how to behave. Doing a vitamin D gene test helps you see if your immune system is getting the right orders. Data indicate that people with specific gene variants are twice as likely to get sick during the winter. For this reason, knowing your DNA is the best way to stay strong all year. Become your own health hero.
Vitamin D must go through several steps in the body before it can help your bones, immune system, and mood. Your genes influence each step. The vitamin D pathway includes:
At dnaPower, we test the most important genetic variations in your pathway. This helps you understand why vitamin D may or may not be working for you.
The Vitamin D Receptor (VDR)
The VDR gene acts like a lock. Vitamin D is the key. If the lock is rusty or broken:
Reduced TCN2 Transport
Vitamin D must travel through your bloodstream to reach your tissues. Genetic differences here can affect:
Vitamin D Activation and Breakdown
Most people hear about the MTHFR gene first. But focusing only on MTHFR is like pressing the gas pedal while ignoring a blocked exhaust pipe.
If your AHCY gene is inefficient, your methylation cycle can stall. Taking more supplements might not help (and could make you feel worse) if the “drain” is blocked.
Sensitivity to High-Protein Diets
Foods like meat, dairy, and eggs are high in methionine. If your AHCY gene is slow, your body struggles to process all that protein. This can lead to inflammation or feeling "heavy" and unwell after big meals.
Sensitivity to Chemicals
Your body uses methylation to detoxify (clean) your liver. If your AHCY activity is low, you might be more sensitive to:
The AHCY gene helps regulate SAMe, a compound that controls your mood and motivation. During long winters or periods of low sunlight, our energy is already tested. If you have a slow AHCY gene, managing stress and fighting off low moods becomes much harder.
Your genes work as a team. Context is everything. We do not test AHCY by itself because that doesn’t give you the full story. We look at it as part of your full methylation pathway, including:
This full picture explains why some people feel worse when they take certain vitamins. If the drain is clogged, adding more water just makes a mess.
Standard blood work doesn’t measure:
This is why you can have “normal” lab results but still feel tired, inflamed, or toxic.
Your dnaPower report gives you a clear roadmap. You will learn:
All these insights are included in our comprehensive totalPower test, with simple explanations and steps you can take immediately.
Simple at-home cheek swab with no needles.
Clear reports that are easy to read and use.
Secure and private testing.
What You Can Do With Your Results
Knowing your TCN2 status helps you pick the right vitamin dose and form. It also helps you plan for better nerve and brain health. All these insights are part of your Total Health Blueprint, which is tailored to your lifestyles.
Staying strong all year is easier when you know exactly what your cells need. A vitamin D gene test reveals the best way to support your mood and your bones. Because everyone is different, this data helps you stop following generic advice that does not work for your DNA. This small change can lead to more energy and a much happier winter season. Your DNA has the answers you have been looking for.
You might notice inflammation, constant fatigue, sensitivity to smells or chemicals, trouble handling stress, or feeling worse when taking B-vitamins.
No. It is a genetic variation. It just means your body processes waste products a little slower than others.
Yes. If your “drain” is slow, adding more methyl-folate supplements can sometimes increase your symptoms instead of fixing them.
Many basic tests only look at MTHFR. To understand AHCY, you need to look at the whole pathway, which fewer companies offer.
No. You can do the test at home with a simple cheek swab. It is designed for wellness and educational purposes.
Ready to find your balance? Fill out the form and connect with our team.
Living in Canada means battling the “winter blues” and long months of limited sunlight. But for many, simply taking extra supplements isn’t enough. The missing link often lies in your vitamin D receptor gene. At dnaPower, we help you look past blood levels to understand how your body actually receives and uses this critical nutrient.
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You can flood your body with Vitamin D, but if your vitamin D receptors aren’t working efficiently, your cells won’t get the message.
Think of Vitamin D as a key and the receptor as the lock. If you have a vitamin D receptor mutation (such as the FokI, BsmI, or TaqI variants), the lock may be “jammed.” This creates a functional vitamin D receptor deficiency, where your body acts deficient even when your blood test numbers look normal.
This is a common frustration for Canadians who take high-dose supplements but still experience:
In a country where UV exposure is minimal for 6 months of the year, efficient VDR function is non-negotiable.
Your VDR gene controls the expression of antimicrobial peptides. If this gene is sluggish, your defense against the flu season is compromised. Read more about key immune function genes.
VDR dictates how much calcium you absorb from your gut. A mutation here can increase the risk of osteoporosis, a major concern for aging Canadians.
Vitamin D receptors are abundant in the brain areas linked to depression. Genetic blockages here can worsen winter mood dips.
| Feature | Details |
|---|---|
| Gene Name | VDR (Vitamin D Receptor) |
| Primary Function | Instructs cells to absorb Calcium & Phosphate; regulates immunity. |
| Sample Type | Simple, non-invasive cheek swab. |
If your test reveals a mutation, you are not powerless. At dnaPower, we guide you on how to increase vitamin D receptor sensitivity through targeted lifestyle changes:
Magnesium & Zinc: These minerals are essential cofactors. Without them, the VDR cannot bind to Vitamin D effectively. Our Mineral Mastery Package pinpoints your specific needs.
Gut Health: Butyrate, a short-chain fatty acid produced by healthy gut bacteria, stimulates VDR expression.
Exercise: Regular movement has been shown to upregulate VDR activity in muscle tissue.
Real Results From Canadian Patients
This was a great experience. Easy to use and the information I gained from this test was amazing. The follow up report review after my test was excellent. It explained how my
genes are affecting my health. I had been struggling to lose weight and now I think I have unlocked the keys to managing my health in a more informed manner. Thank you!
Annette W.
My results review was super informative, helped explain things to me. My consultant suggested diet changes and an array of vitamins to help me with my chronic pain.
Really enjoyed talking with her! Definitely recommended
Donna H.
Terrific experience start to finish. Gained a lot of great info and developed a clear plan for improving. The reports were clear and easy to read. The report review session was extremely valuable.
Scott M.
I would like to thank dnaPower for the experience. I’ve not received this level of customer service in a long time and it’s a breath of fresh air. The overall experience
has been great. My personal information is informative and the ability to speak to someone regarding the results is very effective. They clearly know what they’re doing. I highly recommend them if you’re interested in obtaining the information required to be the ultimate human.
Emery B.
Very happy with how quickly the results were ready and the amazing insight which has already helped me make better decisions for my long-term health.
Sarah D.
The best thing I have ever done. It was so exciting. I have learned so much about myself and it’s like fixing a broken car. My report was awesome, so clear to read and
use. I have already started making changes. I look at this report like a puzzle missing about 20 pieces. I will be working hard on putting the correct pieces back in place for a clear picture. The body is fascinating on how it works. Hard to explain but this gives me goosebumps when I think about it every day. It’s so exciting.
Thanks again, also staff just Fantastic great email response even late at night that’s customer service.
Derek D.
I was not expecting the amount of detail and insight I received from totalPower. I am still digesting all of the information. I have had a lot of light bulb moments while reading my
results and it has given my nurse practitioner some insight to the health issues I have been trying to solve. This is the first step anyone can take towards “health” care. Everyone should do this before they turn 30. So many little changes that you can do for yourself so your “disease” care which be much less in the healthcare system. I just can’t say it enough…..best purchase ever!!
Julie B.
Best thing I’ve ever done, best money ever spent, worth every penny.
Trevor F.
My report review was fantastic! The practitioner took the time to explain my results, and recommend supplements, diet and exercise to maximize my health.
Rob S.
We are beyond impressed with dnaPower! And cannot wait to implement this into our health practice!
Florilège S.
I got my whole family on board with dnaPower and wow what amazing customer service. I have never experienced customer service like that before. It made it so easy to
decide to go with dnaPower. It was very simple to do and within a month the results came back. I was very impressed with everything that came with it. The price was very reasonable. I highly recommend going with dnaPower to get a better idea on your overall health.
Noah M.
My mind was blown with the information I was given on my report. Easy to read, very thorough. Every problem I’ve ever had all makes sense now! I am now supplementing
for my deficiencies and day by day I just keep getting better. I’m 26 and I’ve never felt this good. Life changing. Thank you dnaPower. Highly recommend!
Kyle E.
Knowledge is Power. Understanding your genetics is a fascinating science and I highly recommend dnaPower!
Angela H.
Stop guessing with your dosage. Understanding your vitamin D receptor profile allows you to tailor your intake, whether you need higher doses of D3, specific co-factors like K2, or lifestyle adjustments to boost receptor density.
If you’re still feeling low, read our deep dive on common causes of low Vitamin D.
Ready to beat the Canadian winter? Fill out the form below to order your test kit and optimize your health from the inside out.
USD $375
(Complete 4-in-1 DNA Analysis)
