Discover how your unique methylation genes affect your health with our totalPower 4-in-1 DNA test.
– 250+ genetic variations
– 12+ key methylation genes
– 80+ actionable areas
⭐⭐⭐⭐⭐4.9/5 rating
“Incredible Insights” “Easy to understand”
Unlock the secrets of your DNA to optimize your health.
Discover how your genes influence your diet, health, fitness, and brain wellness.
dietPower
Eat for your DNA
Diet Management
Weight Response
Food Tolerances
Food Taste and Preferences
Vitamins and Supplements
healthPower
Live healthy for your DNA
Power and Endurance
Injury and Recovery
Exercise Performance
Exercise Response
fitPower
Exercise for your DNA
Detoxification
Hormones
Inflammation
Methylation
brainPower
Be proactive for your DNA
Cognitive Resilience
Concussion
Cortisol
Depression
Emotional Eating
Parkinson’s
Methylation is a vital cellular process that affects everything from how your body uses nutrients to how it regulates gene expression. It’s one of the body’s most fundamental biochemical pathways — essential for energy, brain function, detoxification, and overall health.
Methylation genes help regulate how your body uses nutrients, clears toxins, processes hormones, and maintains optimal physical and mental health through gene expression and cellular function
✓Process nutrients – especially B vitamins (B2, B6, B9/folate, B12)
✓Detoxification – via glutathione production and phase II liver detox
✓Hormone metabolism – including estrogen breakdown
✓Mental health – neurotransmitter synthesis and regulation
✓ Cell repair and gene regulation – DNA stability and healthy gene expression
Our comprehensive 4-in-1 DNA test analyzes 12 essential methylation genes. Methylation genes play a key role in how your body processes nutrients, detoxifies, and maintains optimal health — by regulating DNA expression, neurotransmitter balance, and cellular repair.
Helps break down S-adenosylhomocysteine (SAH), supporting homocysteine metabolism and methylation reactions.
Homocysteine
Detoxification
Catechol-O-Methyltransferase
Helps break down catecholamines such as dopamine, norepinephrine, and epinephrine through methylation.
Anxiety
Stress Response
Adds fucose to glycans and influences secretor status, mucosal glycans, and interactions with the gut microbiome.
Gut Health
Inflammatory Bowel Disease
The A1298C variant can affect MTHFR activity and may influence folate-dependent methylation pathways.
Folate metabolism
Heart Health
Uses vitamin B12 and 5-MTHF to help convert homocysteine to methionine, supporting the methylation cycle.
Vitamin B12
Cognition
Helps reactivate methionine synthase by maintaining its vitamin B12 cofactor in an active form.
B12 Deficiency
Fatigue
Transfers one-carbon units from serine into folate metabolism and supports the interconversion of serine and glycine.
DNA Synthesis
Folate Metabolism
Carries vitamin B12 in the bloodstream and supports delivery of the vitamin to cells for cellular use.
B12 Transport
Absorption
Acts as a receptor for active vitamin D and regulates gene expression involved in calcium balance and other cellular functions.
Immunity
Gene regulation
Key Methylation Genes
Genetic Variations
Comprehensive test
Select the test or bundle that matches your goals.
Receive your kit and collect your sample at home. Fast & painless.
Your sample is analyzed in our CLIA & CAP accredited labs.
Explore easy-to-understand reports with actionable insights.
Discover the kind of life-changing insights packed into every 170+ page totalPower DNA report.
✓ 250+ genetic variations analyzed
✓ Personalized action plans for each area
✓ Easy-to-understand visual breakdowns
✓ Science-backed health recommendations
We are not in the business of selling data. We are in the business of helping people live a healthier life using personalized, science-based information.
Methylation is a natural process in your body that helps regulate how your genes function. It supports many important processes, including energy production, detoxification, hormone balance, brain health, and immune function. Your genetics can influence how efficiently your methylation pathways work, which may affect your individual health and nutritional needs.
Our DNA test provides personalized insights into how your body is built to function. You’ll discover how your genes influence key areas such as:
Our test gives you actionable insights into diet, fitness, supplements, and lifestyle choices so you can optimize your health based on your unique DNA.
We test over 250 validated genetic variations across 80+ health categories using our CLIA certified lab and scientifically backed research. Our reports provide highly reliable insights that help guide real, personalized changes for better health, energy, and wellness.
It’s fast, easy, and done at home. The test is mailed to your home. Swab the inside of your cheek, and return your sample in the envelope. You’ll receive your results online in 2–4 weeks with clear, personalized reports. totalPower tests include a report review with a DNA certified consultant.
Ready to find your balance? Fill out the form and connect with our team.
See how your DNA can guide better choices in food, fitness, and life. Join thousands of others who trust dnaPower.
CAD $499 (Complete 4-in-1 DNA Analysis)
✓ 250+ genetic variations analyzed
✓ Personalized action plans for each area
✓ Easy-to-understand visual breakdowns
✓ Science-backed health recommendations
