Unlock Your
Methylation Potential
Discover how your unique methylation genes affect your health with our totalPower 4-in-1 DNA test.
- 250+ genetic variations
- 12+ key methylation genes
- 80+ actionable areas
4.9/5 rating
“Incredible Insights” “Easy to understand”
AS FEATURED IN
Your 4-in-1 Test
Unlock the secrets of your DNA to optimize your health.
Discover how your genes influence your diet, health, fitness, and brain wellness.
CAD $499
Save $846
CAD $1,345
Best Seller
Eat for your DNA
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- Diet Management
- Weight Response
- Food Tolerances
- Food Taste and Preferences
- Vitamins and Supplements
Live healthy for your DNA
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- Power and Endurance
- Injury and Recovery
- Exercise Performance
- Exercise Response
Be proactive for your DNA
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- Cognitive Resilience
- Concussion
- Cortisol
- Depression
- Emotional Eating
- Parkinson’s
What Is Methylation?
Methylation is a vital cellular process that affects everything from how your body uses nutrients to how it regulates gene expression. It’s one of the body’s most fundamental biochemical pathways — essential for energy, brain function, detoxification, and overall health.
What Methylation Genes Do
Methylation genes help regulate how your body uses nutrients, clears toxins, processes hormones, and maintains optimal physical and mental health through gene expression and cellular function
- Process nutrients – especially B vitamins (B2, B6, B9/folate, B12)
- Detoxification – via glutathione production and phase II liver detox
- Hormone metabolism – including estrogen breakdown
- Mental health – neurotransmitter synthesis and regulation
- Cell repair and gene regulation – DNA stability and healthy gene expression
Key Methylation Genes in Your Test
Adenosylhomocysteinase
Breaks down SAH to prevent inhibition of methylation
Catechol-O-Methyltransferase
Breaks down dopamine, estrogen, and stress hormones using methyl groups (SAMe)
Fucosyltransferase 2
Influences B12 absorption and gut microbiome (secretor status)
Methylenetetrahydrofolate Dehydrogenase 1
Balances folate forms; produces methyl donors for DNA synthesis
Methylenetetrahydrofolate Reductase
Supports folate metabolism and BH4 production
Methylenetetrahydrofolate Reductase
Converts folate into active 5-MTHF for methylation
Methionine Synthase
Converts homocysteine to methionine using vitamin B12
Methionine Synthase Reductase
Regenerates MTR enzyme activity to maintain methylation
Serine Hydroxymethyltransferase 1
Converts serine to glycine; supports folate and methyl cycles
Transcobalamin I
Binds and stores vitamin B12 in the bloodstream
Transcobalamin II
Transports active vitamin B12 into cells
Vitamin D Receptor
Regulates gene expression; affects methylation via immune and B12 pathways
Unlock the Power of Your Methylation Genes
Your dnaPower test includes 12 key methylation genes involved in nutrient metabolism, detoxification, and cellular repair. Understanding your genetic variations helps personalize your diet, supplements, and lifestyle for optimal health.
12+
Key Methylation Genes
250+
Genetic Variations
4-in-1
Comprehensive test
What can totalPower DNA Testing do for you?
Eat Right for Your Genes
Target the Vitamins and Supplements You Need
Train Smarter, Not Harder
Understand Your Hormones & Methylation Pathways
Reduce Inflammation & Improve Detoxification
Prevent Future Health Issues
How It Works
Easy at-home cheek swab. Simple, private, and secure
Order Your Kit
Order online and your kit will be delivered to your door.
Send Your Sample
Take a cheek swab and return your sample.
Get Your Results
Receive your results online in 2-4 weeks.
Take Action
Implement healthy changes based on your results.
How dnaPower Is Changing Lives
This was a great experience. Easy to use and the information I gained from this test was amazing. The follow up report review after my test was excellent. It explained how my
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genes are affecting my health. I had been struggling to lose weight and now I think I have unlocked the keys to managing my health in a more informed manner. Thank you!
Annette W.
My results review was super informative, helped explain things to me. My consultant suggested diet changes and an array of vitamins to help me with my chronic pain.
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Really enjoyed talking with her! Definitely recommended
Donna H.
Terrific experience start to finish. Gained a lot of great info and developed a clear plan for improving. The reports were clear and easy to read. The report review session was extremely valuable.
Scott M.
I would like to thank dnaPower for the experience. I’ve not received this level of customer service in a long time and it’s a breath of fresh air. The overall experience
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has been great. My personal information is informative and the ability to speak to someone regarding the results is very effective. They clearly know what they’re doing. I highly recommend them if you’re interested in obtaining the information required to be the ultimate human.
Emery B.
Very happy with how quickly the results were ready and the amazing insight which has already helped me make better decisions for my long-term health.
Sarah D.
The best thing I have ever done. It was so exciting. I have learned so much about myself and it’s like fixing a broken car. My report was awesome, so clear to read and
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use. I have already started making changes. I look at this report like a puzzle missing about 20 pieces. I will be working hard on putting the correct pieces back in place for a clear picture. The body is fascinating on how it works. Hard to explain but this gives me goosebumps when I think about it every day. It’s so exciting.
Thanks again, also staff just Fantastic great email response even late at night that’s customer service.
Derek D.
I was not expecting the amount of detail and insight I received from totalPower. I am still digesting all of the information. I have had a lot of light bulb moments while reading my
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results and it has given my nurse practitioner some insight to the health issues I have been trying to solve. This is the first step anyone can take towards “health” care. Everyone should do this before they turn 30. So many little changes that you can do for yourself so your “disease” care which be much less in the healthcare system. I just can’t say it enough…..best purchase ever!!
Julie B.
Best thing I’ve ever done, best money ever spent, worth every penny.
Trevor F.
My report review was fantastic! The practitioner took the time to explain my results, and recommend supplements, diet and exercise to maximize my health.
Rob S.
We are beyond impressed with dnaPower! And cannot wait to implement this into our health practice!
Florilège S.
I got my whole family on board with dnaPower and wow what amazing customer service. I have never experienced customer service like that before. It made it so easy to
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decide to go with dnaPower. It was very simple to do and within a month the results came back. I was very impressed with everything that came with it. The price was very reasonable. I highly recommend going with dnaPower to get a better idea on your overall health.
Noah M.
My mind was blown with the information I was given on my report. Easy to read, very thorough. Every problem I’ve ever had all makes sense now! I am now supplementing
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for my deficiencies and day by day I just keep getting better. I’m 26 and I’ve never felt this good. Life changing. Thank you dnaPower. Highly recommend!
Kyle E.
Knowledge is Power. Understanding your genetics is a fascinating science and I highly recommend dnaPower!
Angela H.
Explore A Sample of Our Genetic Report
Discover the kind of life-changing insights packed into every 170+ page totalPower DNA report.
170+ Page Comprehensive Analysis
- 250+ genetic variations analyzed
- Personalized action plans for each area
- Easy-to-understand visual breakdowns
- Science-backed health recommendations
Your Privacy Is Our Top Priority
We are not in the business of selling data. We are in the business of helping people live a healthier life using personalized, science-based information.
How totalPower Can Help You Take Control of Your Health
Frequently Asked Questions
Some questions you may have about genetic testing and how it can transform your health jouney
Our DNA test provides personalized insights into how your body is built to function. You’ll discover how your genes influence key areas such as:
- Nutrition – how well you process carbs, fats, proteins, lactose, gluten and key vitamins
- Fitness – your strengths in endurance, power, recovery, and injury risk
- Detox & Hormones – how effectively your body clears toxins and balances hormones
- Mental Health & Inflammation – your resilience to stress and risks for chronic inflammation
Our test gives you actionable insights into diet, fitness, supplements, and lifestyle choices so you can optimize your health based on your unique DNA.
We test over 250 validated genetic variations across 80+ health categories using our CLIA certified lab and scientifically backed research. Our reports provide highly reliable insights that help guide real, personalized changes for better health, energy, and wellness.
It’s fast, easy, and done at home. The test is mailed to your home. Swab the inside of your cheek, and return your sample in the envelope. You’ll receive your results online in 2–4 weeks with clear, personalized reports. totalPower tests include a report review with a DNA certified consultant.
Start Your Path To Better Health
CAD $499
(Complete 4-in-1 DNA Analysis)
- 250+ genetic variations analyzed
- Personalized action plans for each area
- Easy-to-understand visual breakdowns
- Science-backed health recommendations
Unlock the full potential of your health with dnaPower. Since 2008, we’ve empowered individuals to make smarter, data-driven health decisions.
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