Some people thrive under pressure. Others feel overwhelmed, anxious, or “wired-but-tired.” This difference is often genetic. Often called the Warrior vs. Worrier Gene, the COMT Gene mutation test helps explain how your body clears stress chemicals and estrogen. This offers powerful insight into anxiety, sleep, focus, and hormone balance.
The COMT gene (Catechol-O-Methyltransferase) helps break down specific chemicals in your body. Think of it as your body’s “cleanup crew” for stimulation. It regulates:
COMT acts like the body’s “off switch” for stimulation. The speed at which that switch operates affects your nervous system, mood, and hormone balance.
dnaPower tests key COMT variants, which influence how quickly stimulation is cleared from your system.
Neither type is “good” or “bad”; they simply require different support strategies.
The COMT gene is often described as a “mood gene,” but its influence is much broader.
Individuals with slower COMT activity often feel overstimulated in busy environments. They are also more prone to burnout after prolonged periods of stress because their body takes longer to return to baseline.
COMT plays a vital role in estrogen clearance. When estrogen metabolites linger longer, symptoms can feel amplified—even when standard hormone blood tests look normal. This is often linked to:
For "Worriers" (Slow COMT), shutting the brain off at night can be challenging. Racing thoughts and physical tension often prevent deep sleep.
The text discusses how Slow COMT types react to methylated B-vitamins. This explains why the same coffee or supplement can feel helpful for one person and terrible for another. It’s not about willpower, it’s about how your nervous system is wired
You do not need a referral to access this information. We have made the process simple and accessible.
Knowing your COMT type isn’t just interesting trivia; it helps you personalize your daily life. Your report will guide you on:
All these insights are included in our comprehensive totalPower test, with simple explanations and steps you can take immediately.
If anxiety, sleep disruption, burnout, or hormone symptoms haven’t improved with generic advice, your COMT gene may be the missing piece of insight.
Learn whether your body is wired more like a Warrior or a Worrier, so you can support your stress response, energy, and hormones the right way.
Some questions you may have about genetic testing and how it can transform your health jouney
Generally, no. Most standard clinics do not offer preventative genetic testing for COMT. A specialized private test is usually required.
Yes. If you have a Slow COMT mutation, you may struggle to fall asleep because your body hasn’t cleared the day’s adrenaline or dopamine by bedtime.
Once our lab receives your sample, results are typically ready within 3-4 weeks.
No, you do not need a referral to order a test from dnaPower.
While both analyze DNA, dnaPower focuses specifically on health optimization. We provide detailed lifestyle, diet, and fitness recommendations based on your results, with a focus on Canadian health standards and support.
Ready to find your balance? Fill out the form and connect with our team.