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AHCY Gene Mutation Test: The “Drain” of Your Methylation Cycle

Think of your body’s methylation system like a sink. You need a faucet to let water in, but you also need a drain to let it out. The AHCY gene is that drain. Most people focus on the faucet (putting vitamins in). But if the drain is clogged, everything backs up. At dnaPower, our AHCY Gene Mutation Test identifies critical blockages in your detoxification pathways.

This blockage can slow down your detox, drain your energy, and cause inflammation, even if your other genes look “fine.”

What Does the AHCY Gene Do?

The AHCY gene (Adenosylhomocysteinase) is responsible for clearing out a waste product called SAH.

Here is the simple version:

If your AHCY gene works slowly, that waste (SAH) builds up. This acts like a brake on your entire system. It means your body might slow down, even if your vitamin levels look normal on a blood test. You can learn more about how this process works in our guide on what methylation is.

AHCY Gene test

Why This Gene Is Often Overlooked

Most people hear about the MTHFR gene first. But focusing only on MTHFR is like pressing the gas pedal while ignoring a blocked exhaust pipe.

If your AHCY gene is inefficient, your methylation cycle can stall. Taking more supplements might not help (and could make you feel worse) if the “drain” is blocked.

How an AHCY Blockage Affects Your Life

Sensitivity to High-Protein Diets

Foods like meat, dairy, and eggs are high in methionine. If your AHCY gene is slow, your body struggles to process all that protein. This can lead to inflammation or feeling "heavy" and unwell after big meals.

Sensitivity to Chemicals

Your body uses methylation to detoxify (clean) your liver. If your AHCY activity is low, you might be more sensitive to:

  • Chemicals in the air.
  • Alcohol.
  • Certain medications.

Mood & Seasonal Energy

The AHCY gene helps regulate SAMe, a compound that controls your mood and motivation. During long winters or periods of low sunlight, our energy is already tested. If you have a slow AHCY gene, managing stress and fighting off low moods becomes much harder.

How to Get an AHCY Gene Test
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AHCY Does Not Work Alone

Your genes work as a team. Context is everything. We do not test AHCY by itself because that doesn’t give you the full story. We look at it as part of your full methylation pathway, including:

This full picture explains why some people feel worse when they take certain vitamins. If the drain is clogged, adding more water just makes a mess.

Why Blood Tests Don’t Show This

Standard blood work doesn’t measure:

This is why you can have “normal” lab results but still feel tired, inflamed, or toxic.

AHCY Gene Mutation Test
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What You Learn From Our Test

Your dnaPower report gives you a clear roadmap. You will learn:

If your methylation cycle is “backed up.”
Why detox or energy supplements haven’t worked for you in the past.
If you need to change your protein intake.
How to support your body gently, without overloading it.

All these insights are included in our comprehensive totalPower test, with simple explanations and steps you can take immediately.

AHCY Gene Mutation Test in Canada
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Clear the Bottleneck

If you have tried supplements, detox programs, or diet changes but still feel stuck, the missing piece might be your “drain.” Get your DNA test today and discover if the AHCY gene is the bottleneck holding your energy back.

USD $375

(Complete 4-in-1 DNA Analysis)

Frequently Asked Questions

What are common signs of AHCY issues?

You might notice inflammation, constant fatigue, sensitivity to smells or chemicals, trouble handling stress, or feeling worse when taking B-vitamins.

Is an AHCY mutation a disease?

No. It is a genetic variation. It just means your body processes waste products a little slower than others.

Can this affect how I handle supplements?

Yes. If your “drain” is slow, adding more methyl-folate supplements can sometimes increase your symptoms instead of fixing them.

Why isn’t AHCY tested more often?

Many basic tests only look at MTHFR. To understand AHCY, you need to look at the whole pathway, which fewer companies offer.

Do I need a doctor to take this test?

No. You can do the test at home with a simple cheek swab. It is designed for wellness and educational purposes.

Ready to find your balance? Fill out the form and connect with our team.